Drs. S. Weir Mitchell and Edward T. Reichert on the Poison of Heloderma Suspectum (Cope), the Gila Monster
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Water supplementation affects the behavioral and physiological ecology of Gila monsters (Heloderma suspectum) in the Sonoran Desert.
In desert species, seasonal peaks in animal activity often correspond with times of higher rainfall. However, the underlying reason for such seasonality can be hard to discern because the rainy season is often associated with shifts in temperature as well as water and food availability. We used a combination of the natural climate pattern of the Sonoran Desert and periodic water supplementation...
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The data presented here is related to the research article entitled "Characterization of the gila monster (Heloderma suspectum suspectum) venom proteome" by Sanggaard et al. in Journal of Proteomics [1]. The gila monster venom was collected, analyzed by 2D-gel electrophoresis and after Coomassie-Brilliant Blue staining the major spots were excised, subjected to in-gel trypsin digestion, and ana...
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Reptile venoms are complex cocktails of bioactive molecules, including peptides. While the drug discovery potential of most species remains unrealized, many are endangered and afforded protection under international treaties. In this study, we describe how potential clinically important bioactive peptides and their corresponding mRNAs can be structurally characterized from single, small samples...
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The Gila monster Heloderma suspectum is an active forager in an environment that, at times, can be extremely hot and arid. Thus, Gila monsters face extreme thermostatic and hydrostatic demands. For a desert ectotherm routinely risking dehydration, evaporative water loss (EWL) is typically viewed as detrimental. Yet evaporation simultaneously dehydrates and cools an animal. We explored EWL in Gi...
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A wide variety of sex determination systems exist among squamate reptiles. They can therefore serve as an important model for studies of evolutionary transitions among particular sex determination systems. However, we still have only a limited knowledge of sex determination in certain important lineages of squamates. In this respect, one of the most understudied groups is the family Helodermati...
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